*All games start at 7 p.m. Nov. 15 unless noted.
Division 1
Region 1
Hudsonville 35, Howell 6
Region 2
Rochester Adams 21, Grand Blanc 14
Region 3
Detroit Catholic Central 35, Belleville 21
Region 4
Detroit Cass Tech 21, Macomb Dakota 14
Division 2
Region 1
Byron Center 52, Portage Central 14
Region 2
East Lansing 49, Saginaw Heritage 27
Region 3
Orchard Lake St. Mary's 27, Gibraltar Carlson 3
Region 4
Birmingham Groves 21, Warren De La Salle Collegiate 19
Division 3
Region 1
DeWitt 70, Petoskey 34
Region 2
Zeeland West 36, GR Forest Hills Central 20
Region 3
Mason 22, Walled Lake Western 17
Region 4
Detroit Martin Luther King 34, River Rouge 0
Division 4
Region 1
Grand Rapids South Christian 28, Whitehall 21
Region 2
Niles 37, Portland 34
Region 3
Goodrich 42, Haslett 13
Region 4
Harper Woods 48, Macomb Lutheran North 3
Division 5
Region 1
Frankenmuth 35, Gladwin 0
Region 2
Grand Rapids Catholic Central 21, Kalamazoo Hackett Catholic Prep 14
Region 3
Pontiac Notre Dame Prep 45, Armada 19
Region 4
Flat Rock 41, AA Father Gabriel Richard 0
Division 6
Region 1
Boyne City 34, Reed City 21
Region 2
Lansing Catholic 49, Newaygo 36
Region 3
Jackson Lumen Christi 42, Constantine 6
Region 4
Marine City 52, Detroit Central 26
Division 7
Region 1
North Muskegon 23, Menominee 0
Region 2
Millington 28, Pewamo-Westphalia 0
Region 3
Schoolcraft 28, Hudson 16
Region 4
Monroe SMCC 55, Leslie 18
Division 8
Region 1
Beal City 14, Iron Mountain 7
Region 2
Fowler 25, Harbor Beach 7
Region 3
Decatur 41, Reading 0
Region 4
Riverview Gabriel Richard 30, Detroit Loyola 12